Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18706356 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL29957424 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL29957054 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL29956300 | 0.78 | QRFPR (0.46) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL29953365 | 0.77 | QRFPR (0.47) | ALDH1A1MEN1KMT2APDE4ASIGMAR1 | |
| SCHEMBL29951283 | 0.76 | ALDH1A1 (0.43) | ALDH1A1CYP2D6SLC6A2SLC6A4MAPK1 | |
| SCHEMBL29955155 | 0.75 | QRFPR (0.54) | ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL14201717 | 0.75 | MEN1 (0.62) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL29952597 | 0.74 | HRH3 (0.68) | ALDH1A1MAPTHRH4HRH3ABCB11 | |
| SCHEMBL3979242 | 0.74 | HRH3 (0.68) | ALDH1A1MAPTHRH4HRH3ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |