Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953365 | 0.96 | QRFPR (0.47) | QRFPRENPP2DRD4SIGMAR1IDO1 | |
| SCHEMBL29953128 | 0.88 | PDE4D (0.41) | QRFPRENPP2PDE4B | |
| SCHEMBL1024456 | 0.80 | ENPP2 (0.46) | ENPP2IDO1CA1CA2HPGD | |
| SCHEMBL26108979 | 0.78 | KDM4E (0.36) | QRFPRENPP2CA1CA2 | |
| SCHEMBL29953633 | 0.78 | NAAA (0.38) | IDO1 | |
| SCHEMBL29956506 | 0.78 | ALDH1A1 (0.58) | SIGMAR1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL29951416 | 0.77 | DRD4 (0.47) | QRFPRENPP2DRD4SIGMAR1TMEM97 | |
| SCHEMBL14201717 | 0.77 | MEN1 (0.62) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL18529899 | 0.75 | PDE4A (0.46) | ENPP2IDO1CA1CA2PDE4B | |
| SCHEMBL21396 | 0.75 | ENPP2 (0.44) | ENPP2CA1CA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |