Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954950 | 0.81 | HTR1A (0.42) | ALDH1A1ALOX15 | |
| SCHEMBL29956506 | 0.76 | ALDH1A1 (0.58) | ALDH1A1CYP2D6MAPK1SLC6A2SLC6A4 | |
| SCHEMBL29953347 | 0.76 | BCHE (0.41) | ALDH1A1ALOX15 | |
| SCHEMBL18706356 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL21396 | 0.74 | ENPP2 (0.44) | ALDH1A1 | |
| SCHEMBL29952179 | 0.74 | CHRM2 (0.50) | — | |
| SCHEMBL29951579 | 0.74 | ACHE (0.47) | ALOX15 | |
| SCHEMBL29958472 | 0.73 | SLC6A2 (0.48) | SLC6A2SLC6A4DRD2DRD3 | |
| SCHEMBL29954644 | 0.72 | SLC6A2 (0.44) | SLC6A2SLC6A4 | |
| SCHEMBL29953874 | 0.71 | LPL (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |