SCHEMBL29956586

SCHEMBL29956586

O=Cc1cnc(OC(F)F)cn1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 2/20 0.34
KCNJ1 P48048 1/20 0.34
DAO P14920 1/20 0.32
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29005313 0.85 KCNJ1 (0.33) KCNJ1
SCHEMBL20685033 0.74 KCNJ1 (0.35) DRD1KCNJ1ALDH1A1L3MBTL1
SCHEMBL29935892 0.74 TUBB4A (0.49) KCNJ1ALDH1A1
SCHEMBL14832858 0.74 TUBB4A (0.49) KCNJ1ALDH1A1
SCHEMBL1825784 0.73 KCNJ1 (0.48) KCNJ1ALDH1A1
SCHEMBL20489794 0.72 DRD1 (0.49) DRD1KCNJ1ALDH1A1L3MBTL1
SCHEMBL29416918 0.72 ALDH1A1 (0.54) DRD1KCNJ1DAOALDH1A1L3MBTL1
SCHEMBL7999562 0.72 ALDH1A1 (0.54) DRD1KCNJ1DAOALDH1A1L3MBTL1
SCHEMBL29957580 0.72 DRD1 (0.33) DRD1
SCHEMBL21275800 0.71 DAO (0.32) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed