Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ATF4 | P18848 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953623 | 0.95 | SMN1; SMN2 (0.67) | HPGDHTTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL29958458 | 0.94 | SMN1; SMN2 (0.70) | HPGDHTTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL2555225 | 0.91 | CYP1A2 (0.54) | HPGDHTTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL29953444 | 0.87 | CNR2 (0.59) | HPGDHTTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL29952903 | 0.83 | ALDH1A1 (0.71) | HPGDHTTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL29950838 | 0.82 | SMN1; SMN2 (0.49) | HPGDSMN1; SMN2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL15638454 | 0.81 | RAB9A (0.67) | HPGDHTTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL12629119 | 0.81 | CYP1A2 (0.66) | HPGDHTTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL15272377 | 0.81 | HPGD (0.64) | HPGDHTTRAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL15329632 | 0.80 | ALDH1A1 (0.58) | HTTRAB9ASMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |