Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953623 | 0.99 | SMN1; SMN2 (0.67) | SMN1; SMN2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL29956675 | 0.94 | HPGD (0.61) | SMN1; SMN2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL2555225 | 0.88 | CYP1A2 (0.54) | SMN1; SMN2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL29956853 | 0.84 | ALDH1A1 (0.83) | SMN1; SMN2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL29955306 | 0.84 | ALDH1A1 (0.83) | SMN1; SMN2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL29952142 | 0.83 | ALDH1A1 (0.81) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7515503 | 0.81 | KMT2A (0.80) | SMN1; SMN2CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL29953444 | 0.81 | CNR2 (0.59) | SMN1; SMN2CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL2751507 | 0.81 | CYP1A2 (0.74) | SMN1; SMN2CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL14112024 | 0.80 | KMT2A (0.77) | SMN1; SMN2CYP1A2CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |