Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266872 | 0.79 | GABRP (0.53) | LOXL2CYP2A6GABRPGABRDGABRA1 | |
| SCHEMBL29956124 | 0.76 | CYP2A6 (0.42) | LOXL2CYP2A6MAPTKDM4EALDH1A1 | |
| SCHEMBL1788955 | 0.76 | CYP2A6 (0.42) | LOXL2CYP2A6MAPTKDM4EALDH1A1 | |
| SCHEMBL2465473 | 0.76 | KDM4E (0.64) | CYP2A6MAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL24860323 | 0.73 | MAOA (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL20595429 | 0.72 | L3MBTL1 (0.46) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL31108064 | 0.72 | L3MBTL1 (0.46) | NPC1MAPTRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL30488441 | 0.72 | GRM5 (0.43) | LOXL2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL5364336 | 0.72 | GRM5 (0.43) | LOXL2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28230139 | 0.70 | CYP3A4 (0.55) | MAPTSMN1; SMN2L3MBTL1GRM5PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |