Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ATF4 | P18848 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955306 | 1.00 | ALDH1A1 (0.83) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL29952142 | 0.99 | ALDH1A1 (0.81) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL29952903 | 0.93 | ALDH1A1 (0.71) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL2556699 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL29958458 | 0.84 | SMN1; SMN2 (0.70) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL25893880 | 0.84 | KMT2A (0.69) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL3456069 | 0.83 | SMN1; SMN2 (0.76) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL19659333 | 0.83 | KMT2A (0.69) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL19134217 | 0.83 | ATF4 (0.86) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL25893839 | 0.83 | SMN1; SMN2 (0.76) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |