Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
| ▸ | TYK2 | P29597 | 2/20 | 0.30 |
| ▸ | JAK3 | P52333 | 2/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955666 | 0.92 | KDM4E (0.41) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL29954922 | 0.81 | DYRK1A (0.35) | KDM4EMAPTKMT2AALDH1A1JAK2 | |
| SCHEMBL29951956 | 0.81 | TRIM24 (0.41) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29956872 | 0.77 | HTT (0.33) | MEN1KMT2AALDH1A1JAK2JAK1 | |
| SCHEMBL29954538 | 0.77 | FFAR2 (0.34) | JAK2JAK1TYK2JAK3DYRK1A | |
| SCHEMBL29953493 | 0.75 | MAPT (0.41) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29952619 | 0.75 | TRIM24 (0.43) | KDM4EMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29952259 | 0.75 | STING1 (0.36) | KDM4EMAPTALDH1A1 | |
| SCHEMBL29957135 | 0.74 | ERN1 (0.37) | KDM4EMAPTALDH1A1JAK2JAK1 | |
| SCHEMBL29953410 | 0.72 | CYP1A2 (0.46) | KDM4EMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |