Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | CXCR5 | P32302 | 4/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306602 | 0.81 | CXCR5 (0.59) | CXCR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20563741 | 0.81 | ALB (0.46) | CXCR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12760784 | 0.78 | ALDH1A1 (0.43) | CXCR5G6PDCASP7CASP6PDE4A | |
| SCHEMBL5791812 | 0.77 | ALB (0.45) | CXCR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3465394 | 0.77 | CXCR5 (0.55) | CXCR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30159711 | 0.76 | PDE4B (0.51) | PDE4APDE4BPDE4CPDE4DMAPK1 | |
| SCHEMBL10590612 | 0.76 | PTGDR2 (0.43) | CXCR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29956893 | 0.75 | CA1 (0.39) | CXCR5KDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL1489523 | 0.74 | MMP2 (0.57) | MMP2G6PDCASP7CASP6KDM4E | |
| SCHEMBL3309536 | 0.74 | CXCR5 (0.52) | CXCR5PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077309-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas Operations, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |