Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958105 | 0.83 | LPL (0.44) | ENPP2EPHX1LPLLIPGLTA4H | |
| SCHEMBL3979242 | 0.82 | HRH3 (0.68) | HRH3HRH4PARP1LPLLIPG | |
| SCHEMBL29952597 | 0.82 | HRH3 (0.68) | HRH3HRH4PARP1LPLLIPG | |
| SCHEMBL29957424 | 0.78 | ALDH1A1 (0.45) | HRH3HRH4ALDH1A1LMNAMAPT | |
| SCHEMBL7603670 | 0.76 | HRH3 (0.73) | HRH3HRH4PARP1SLC18A3LTA4H | |
| SCHEMBL1723229 | 0.76 | ENPP2 (0.60) | ENPP2LPLLIPGALDH1A1CXCR1 | |
| SCHEMBL29957867 | 0.76 | HRH3 (0.55) | HRH3HRH4PARP1LTA4HALDH1A1 | |
| SCHEMBL19444739 | 0.76 | HRH4 (0.51) | HRH3HRH4PARP1EPHX1SLC18A3 | |
| SCHEMBL30809701 | 0.76 | HRH4 (0.51) | HRH3HRH4PARP1EPHX1SLC18A3 | |
| SCHEMBL13460105 | 0.76 | HRH3 (0.54) | HRH3HRH4PARP1SLC18A3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |