Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952833 | 0.87 | KMT2A (0.50) | GAAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL15330913 | 0.86 | HTT (0.62) | KMT2AHRH3 | |
| SCHEMBL15332099 | 0.86 | CRHBP (0.64) | MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL29955246 | 0.84 | HTR7 (0.64) | MEN1KMT2AKDM4EHRH3LMNA | |
| SCHEMBL28191613 | 0.84 | GAA (0.66) | GAAMEN1KMT2APOLBKDM4E | |
| SCHEMBL16884151 | 0.82 | GAA (0.63) | GAAMEN1KMT2AKDM4E | |
| SCHEMBL3377384 | 0.81 | KDM4E (0.64) | GAAMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL5786740 | 0.80 | GAA (0.69) | GAAMEN1KMT2APOLBKDM4E | |
| SCHEMBL4150936 | 0.80 | GAA (0.69) | GAAMEN1KMT2APOLBKDM4E | |
| SCHEMBL8327595 | 0.80 | ALDH1A1 (0.66) | GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |