Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29725216 | 0.88 | KMT2A (0.50) | KMT2AKDM4EMEN1SMN1; SMN2TP53 | |
| SCHEMBL21550767 | 0.88 | KMT2A (0.50) | KMT2AKDM4EMEN1SMN1; SMN2TP53 | |
| SCHEMBL29956962 | 0.87 | GAA (0.59) | KMT2AKDM4EMEN1LMNATDP1 | |
| SCHEMBL29955246 | 0.83 | HTR7 (0.64) | KMT2AKDM4EMEN1CRHBPCRHR2 | |
| SCHEMBL9996727 | 0.81 | KDM4E (0.64) | KDM4EHTTLMNAGAA | |
| SCHEMBL2933199 | 0.81 | CRHBP (0.50) | KMT2AKDM4EMEN1CRHBPCRHR2 | |
| SCHEMBL520005 | 0.81 | LMNA (0.57) | KMT2AMEN1CRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL13559777 | 0.81 | CHKA (0.56) | KMT2AKDM4ECRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL15330913 | 0.80 | HTT (0.62) | KMT2ASMN1; SMN2MAPK1HTT | |
| SCHEMBL15332099 | 0.80 | CRHBP (0.64) | KMT2AKDM4EMEN1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |