Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363014 | 1.00 | ERN1 (0.46) | ERN1TDP1MEN1LMNATHRB | |
| Water SCHEMBL28915146 | 0.97 | ERN1 (0.45) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL17006121 | 0.86 | ERN1 (0.41) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL1694767 | 0.83 | ALDH1A1 (0.50) | ERN1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL19920245 | 0.83 | KDM4E (0.42) | ERN1KDM4EALDH1A1PTPN1NFE2L2 | |
| SCHEMBL96915 | 0.82 | NFE2L2 (0.54) | ERN1KDM4EALDH1A1PTPN1NFE2L2 | |
| SCHEMBL29824365 | 0.82 | NFE2L2 (0.54) | ERN1KDM4EALDH1A1PTPN1NFE2L2 | |
| SCHEMBL18181691 | 0.82 | KDM4E (0.44) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL65723 | 0.82 | ERN1 (0.56) | ERN1KDM4EALDH1A1PTPN1NFE2L2 | |
| SCHEMBL24014740 | 0.78 | ERN1 (0.42) | ERN1TDP1MEN1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |