Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29824365 | 1.00 | NFE2L2 (0.54) | NFE2L2ERN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9640276 | 0.91 | NFE2L2 (0.56) | NFE2L2ERN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8072738 | 0.89 | NFE2L2 (0.60) | NFE2L2ERN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL505574 | 0.84 | PIM1 (0.50) | NFE2L2ERN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2774294 | 0.82 | KIF11 (0.44) | NFE2L2ERN1ALDH1A1KDM4E | |
| SCHEMBL4363014 | 0.82 | ERN1 (0.46) | NFE2L2ERN1ALDH1A1KDM4EPTPN1 | |
| SCHEMBL29957006 | 0.82 | ERN1 (0.46) | NFE2L2ERN1ALDH1A1KDM4EPTPN1 | |
| SCHEMBL18181691 | 0.80 | KDM4E (0.44) | NFE2L2ERN1ALDH1A1KDM4EPTPN1 | |
| SCHEMBL65723 | 0.80 | ERN1 (0.56) | NFE2L2ERN1ALDH1A1KDM4EPTPN1 | |
| Water SCHEMBL28915146 | 0.80 | ERN1 (0.45) | NFE2L2ERN1ALDH1A1KDM4EPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2825 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103371-B | EGFR inhibitor and preparation method and application thereof | SHANDONG NEW TIME PHARMACEUTICAL Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-116606265-B | Protocatechu derivative and synthesis method and application thereof | 山西大学 | 2025-05-02 | — | — | CN | claimed |
| CN-119899122-A | Cyclobutylmethyl and phenyl substituted curcumin derivative and preparation method and application thereof | 常州大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119119116-A | Rhein phosphoryl derivative and synthetic method and application thereof | 甘肃中医药大学 | 2024-12-13 | — | — | CN | claimed |
| CN-118852032-A | Alpha, beta-unsaturated ketone derivative, preparation method and application thereof | 赣南医科大学 | 2024-10-29 | — | — | CN | claimed |
| CN-115772110-B | Method for preparing potassium ion competitive blocker non-surafaxin intermediate | 沈阳药科大学 | 2024-08-23 | — | — | CN | claimed |
| CN-118496215-A | Polyhydroxylated onium derivative with disubstituted benzene ring, preparation method and medical application thereof | 中国药科大学 | 2024-08-16 | — | — | CN | claimed |
| CN-118459420-A | Thiazolinone compound containing multiple halogen atoms and preparation method thereof | 南京工业大学 | 2024-08-09 | — | — | CN | claimed |
| CN-118459422-A | Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof | 南京工业大学 | 2024-08-09 | — | — | CN | claimed |
| CN-118103371-A | EGFR inhibitor and preparation method and application thereof | 山东新时代药业有限公司 | 2024-05-28 | — | — | CN | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| WO-1998034115-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| WO-1998034111-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| EP-0497796-B1 | METHOD OF PREPARATION OF FLUOROBENZENES | HOECHST AG (DE) | 1994-06-22 | — | — | EP | claimed |
| US-5264094-A | Process for the preparation of fluorobenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-23 | — | — | US | claimed |
| EP-0497796-A1 | METHOD OF PREPARATION OF FLUOROBENZENES. | HOECHST AG (DE) | 1992-08-12 | — | — | EP | claimed |
| WO-1991006518-A1 | METHOD OF PREPARATION OF FLUOROBENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-16 | — | — | WO | claimed |
| US-4868241-A | POLYVINYL ALCOHOL MODIFIED WITH BENZOIC ACID DERIVATIVE | AMERICAN CYANAMID COMPANY (US) | 1989-09-19 | — | — | US | claimed |
| EP-0231922-A2 | Electron beam and X-ray resists | AMERICAN CYANAMID COMPANY (US) | 1987-08-12 | — | — | EP | claimed |
| US-4614833-A | 2-halo-pyridines | LACER, S.A. (ES) | 1986-09-30 | — | — | US | claimed |