Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957006 | 1.00 | ERN1 (0.46) | ERN1TDP1MEN1LMNATHRB | |
| Water SCHEMBL28915146 | 0.97 | ERN1 (0.45) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL17006121 | 0.86 | ERN1 (0.41) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL1694767 | 0.83 | ALDH1A1 (0.50) | ERN1MEN1LMNAKMT2AKDM4E | |
| SCHEMBL19920245 | 0.83 | KDM4E (0.42) | ERN1KDM4EALDH1A1PTPN1NFE2L2 | |
| SCHEMBL96915 | 0.82 | NFE2L2 (0.54) | ERN1KDM4EALDH1A1PTPN1NFE2L2 | |
| SCHEMBL29824365 | 0.82 | NFE2L2 (0.54) | ERN1KDM4EALDH1A1PTPN1NFE2L2 | |
| SCHEMBL18181691 | 0.82 | KDM4E (0.44) | ERN1TDP1MEN1LMNATHRB | |
| SCHEMBL65723 | 0.82 | ERN1 (0.56) | ERN1KDM4EALDH1A1PTPN1NFE2L2 | |
| SCHEMBL24014740 | 0.78 | ERN1 (0.42) | ERN1TDP1MEN1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400575-A1 | POLYCYCLIC COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | UNIV BARCELONA (ES) | 2024-12-05 | — | — | US | disclosed |
| US-20240068009-A1 | SUBSTITUTED IMIDAZO[1,2-a]PYRAZINES AS LUCIFERASE SUBSTRATES | PROMEGA CORPORATION | 2024-02-29 | — | — | US | disclosed |
| EP-3810572-B1 | POLYCYCLIC COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | UNIV BARCELONA (ES) | 2023-11-15 | — | — | EP | disclosed |
| US-11781168-B2 | Process for preparing substituted imidazo[1,2-α]pyrazines | PROMEGA CORPORATION (US) | 2023-10-10 | — | — | US | disclosed |
| US-11542397-B2 | Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device | TOKYO OHKA KOGYO CO., LTD. (JP) | 2023-01-03 | — | — | US | disclosed |
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |
| US-20210309866-A1 | LIQUID COMPOSITION, QUANTUM DOT-CONTAINING FILM, OPTICAL FILM, LIGHT-EMITTING DISPLAY ELEMENT PANEL, AND LIGHT-EMITTING DISPLAY DEVICE | TOKYO OHKA KOGYO CO., LTD. (JP) | 2021-10-07 | — | — | US | disclosed |
| US-20210254128-A1 | COELENTERAZINE ANALOGUES | PROMEGA CORPORATION | 2021-08-19 | — | — | US | disclosed |
| CN-112888674-A | Polycyclic compounds as soluble epoxide hydrolase inhibitors | 巴塞罗那大学 | 2021-06-01 | — | — | CN | disclosed |
| US-11015216-B2 | Substituted imidazo[1,2-a]pyrazines as luciferase substrates | PROMEGA CORPORATION (US) | 2021-05-25 | — | — | US | disclosed |
| US-20050171216-A1 | Germicidal compositions containing phthalaldehyde mixtures and methods of using such compositions for disinfection or sterilization | ETHICON, INC. | 2005-08-04 | — | — | US | disclosed |
| US-20050171215-A1 | Germicidal compositions containing halogenated phthalaldehyes, and methods of using such compositions for disinfection or sterilization | ETHICON, INC. | 2005-08-04 | — | — | US | disclosed |
| US-20050171121-A1 | Germicidal compositions containing phenylmalonaldehyde-type compounds, or mixtures of phenylmalonaldehyde-type compounds and phthalaldehydes, and methods of using such compositions for disinfection or sterilization | ETHICON, INC. | 2005-08-04 | — | — | US | disclosed |
| US-20050171201-A1 | Alpha-hydroxy sulfonate aldehydes, germicidal compositions containing the alpha-hydroxy sulfonate aldehydes, or mixtures of alpha-hydroxy sulfonate aldehydes and phthalaldehydes, and methods of using the compounds or compositions for disinfection or sterilization | ETHICON, INC. | 2005-08-04 | — | — | US | disclosed |
| EP-1559435-A1 | Germicidal compositions containing phthalaldehyde mixtures and methods of using such compositions for disinfection or sterilization | Ethicon, Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| EP-1559704-A1 | Synthesis of 4-substituted phthalaldehyde | ETHICON, INC. (US) | 2005-08-03 | — | — | EP | disclosed |
| US-6891069-B1 | Synthesis of 4-substituted phthalaldehyde | ETHICON, INC. (US) | 2005-05-10 | — | — | US | disclosed |
| US-6780561-B2 | FOR FORMING PROTECTIVE FILM OR AN INSULATING FILM FOR A SEMICONDUCTOR ELEMENT OR A CIRCUIT BOARD SUCH AS A PRINTED BOARD | KANSAI PAINT CO., LTD. (JP) | 2004-08-24 | — | — | US | disclosed |
| US-20030143480-A1 | For forming protective film or an insulating film for a semiconductor element or a circuit board such as a printed board | KANSAI PAINT CO., LTD. (JP) | 2003-07-31 | — | — | US | disclosed |
| US-5985913-A | GENE EXPRESSION AND CELL GROWTH FACTORS FOR BIOSYNTHESIS | OSI PHARMACEUTICALS, INC. (US) | 1999-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171216-A1 | Germicidal compositions containing phthalaldehyde mixtures and methods of using such compositions for disinfection or sterilization | ALPG, DDT, DHODH | ERN1 4108/4885TDP1 2185/4885MEN1 2583/4885 |
| US-11781168-B2 | Process for preparing substituted imidazo[1,2-α]pyrazines | CYP4Z1, CYP2E1, CYP2F1 | ERN1 1352/4885TDP1 3198/4885MEN1 1426/4885 |
| US-20210254128-A1 | COELENTERAZINE ANALOGUES | AADAC, GLB1, PGLS | ERN1 2555/4885TDP1 4236/4885MEN1 1613/4885 |
| US-20050171215-A1 | Germicidal compositions containing halogenated phthalaldehyes, and methods of using such compositions for disinfection or sterilization | ALPG, G6PD, PGLS | ERN1 4647/4885TDP1 2191/4885MEN1 1571/4885 |
| US-11015216-B2 | Substituted imidazo[1,2-a]pyrazines as luciferase substrates | GLB1, PGLS, AADAC | ERN1 1624/4885TDP1 3343/4885MEN1 1673/4885 |
| US-20050171201-A1 | Alpha-hydroxy sulfonate aldehydes, germicidal compositions containing the alpha-hydroxy sulfonate aldehydes, or mixtures of alpha-hydroxy sulfonate aldehydes and phthalaldehydes, and methods of using the compounds or compositions for disinfection or sterilization | TST, STS, BPNT1 | ERN1 3532/4885TDP1 707/4885MEN1 2654/4885 |
| US-20240068009-A1 | SUBSTITUTED IMIDAZO[1,2-a]PYRAZINES AS LUCIFERASE SUBSTRATES | PGLS, AADAC, GLB1 | ERN1 1806/4885TDP1 3422/4885MEN1 2077/4885 |
| US-20050171121-A1 | Germicidal compositions containing phenylmalonaldehyde-type compounds, or mixtures of phenylmalonaldehyde-type compounds and phthalaldehydes, and methods of using such compositions for disinfection or sterilization | APEH, ALPG, DDT | ERN1 4218/4885TDP1 2150/4885MEN1 2950/4885 |
| US-20240400575-A1 | POLYCYCLIC COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EPHX1, EPHX2, NCEH1 | ERN1 1004/4885TDP1 2727/4885MEN1 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.