Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282687 | 0.80 | CTSK (0.41) | CTSKDGAT1TDP1CA1CA7 | |
| SCHEMBL30154343 | 0.76 | MEN1 (0.35) | CTSKDGAT1TDP1CA1CA7 | |
| SCHEMBL6292986 | 0.74 | TDP1 (0.37) | CTSKDGAT1TDP1CA1CA7 | |
| SCHEMBL25874746 | 0.73 | CTSK (0.32) | CTSKDGAT1TDP1CA1CA7 | |
| SCHEMBL2187338 | 0.72 | NPC1 (0.36) | CTSKDGAT1TDP1CA1CA7 | |
| SCHEMBL2911305 | 0.72 | CTSS (0.40) | CTSKDGAT1TDP1MEN1KMT2A | |
| SCHEMBL2558818 | 0.70 | PTPN11 (0.44) | CTSKDGAT1TDP1MAOAMAOB | |
| SCHEMBL293062 | 0.70 | CTSK (0.40) | CTSKDGAT1TDP1MAOAMAOB | |
| SCHEMBL10883543 | 0.68 | CTSK (0.39) | CTSKDGAT1TDP1MAOAMAOB | |
| SCHEMBL132657 | 0.68 | DGAT1 (0.42) | CTSKDGAT1TDP1CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |