Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955402 | 0.93 | MAPT (0.44) | MAPTPSMB5ABCB1KDM4EHSD17B10 | |
| SCHEMBL29951429 | 0.86 | APOL1 (0.33) | PSMB5KDM4ENR1I2KDM4BCHRM1 | |
| SCHEMBL29951956 | 0.83 | TRIM24 (0.41) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL29957701 | 0.82 | ALDH1A1 (0.37) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29954922 | 0.80 | DYRK1A (0.35) | MAPTKDM4EHSD17B10ALDH1A1KMT2A | |
| SCHEMBL29957135 | 0.79 | ERN1 (0.37) | MAPTPSMB5KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29957489 | 0.79 | SIRT1 (0.46) | MAPTKDM4EHSD17B10ALDH1A1KMT2A | |
| SCHEMBL29951584 | 0.78 | APOL1 (0.34) | — | |
| SCHEMBL29952619 | 0.77 | TRIM24 (0.43) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL29952685 | 0.75 | MAPT (0.50) | MAPTABCB1KDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |