Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952259 | 0.94 | STING1 (0.36) | STING1KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL29951956 | 0.83 | TRIM24 (0.41) | DYRK1AKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL29957069 | 0.81 | KDM4E (0.38) | DYRK1AKMT2AKDM4EMAPTJAK2 | |
| SCHEMBL29953493 | 0.80 | MAPT (0.41) | KMT2AKDM4EMAPTALDH1A1GAA | |
| SCHEMBL29955937 | 0.77 | AR (0.32) | DYRK1AKMT2ATDP1ALDH1A1 | |
| SCHEMBL29957613 | 0.77 | NOS2 (0.40) | DYRK1A | |
| SCHEMBL29952619 | 0.77 | TRIM24 (0.43) | KMT2AKDM4EMAPTALDH1A1GAA | |
| SCHEMBL29951429 | 0.75 | APOL1 (0.33) | KDM4ETDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29956616 | 0.74 | MEN1 (0.41) | DYRK1AKMT2AKDM4EL3MBTL1TDP1 | |
| SCHEMBL29955666 | 0.73 | KDM4E (0.41) | KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |