Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | KLK8 | O60259 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953323 | 0.85 | LRRK2 (0.50) | LRRK2LIPEHTR1ADRD2HTR6 | |
| SCHEMBL29957711 | 0.83 | LIPE (0.69) | LIPEHTR1ADRD2HTR6MEN1 | |
| SCHEMBL29957888 | 0.83 | LIPE (0.47) | LRRK2LIPEKDM4EHSD17B10LMNA | |
| SCHEMBL1753346 | 0.83 | LIPE (0.68) | LRRK2LIPEKDM4EMAPTLMNA | |
| SCHEMBL29951117 | 0.81 | ENPP2 (0.55) | LIPEHTR1AHTR6ENPP2 | |
| SCHEMBL17858634 | 0.81 | MRGPRX4 (0.55) | LRRK2HTR1ADRD2HTR6KDM4E | |
| SCHEMBL171231 | 0.81 | LMNA (0.60) | LRRK2HTR1ADRD2KDM4EMEN1 | |
| SCHEMBL2038082 | 0.81 | LRRK2 (0.50) | LRRK2HTR1ADRD2HTR6KDM4E | |
| SCHEMBL29538704 | 0.80 | LRRK2 (0.50) | LRRK2HTR1ADRD2HTR6KDM4E | |
| SCHEMBL2562185 | 0.79 | LIPE (0.53) | LIPEMEN1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |