Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951363 | 1.00 | LMNA (0.48) | LMNAHSD17B10MAPK1MAPTMITF | |
| SCHEMBL29952419 | 0.88 | LMNA (0.51) | LMNAHSD17B10MAPK1HPGDHTT | |
| SCHEMBL29952820 | 0.88 | LMNA (0.51) | LMNAHSD17B10MAPK1HPGDHTT | |
| SCHEMBL29957231 | 0.87 | KMT2A (0.51) | LMNAHSD17B10MAPTTSHRALDH1A1 | |
| SCHEMBL29957881 | 0.87 | KMT2A (0.51) | LMNAHSD17B10MAPTTSHRALDH1A1 | |
| SCHEMBL29957138 | 0.80 | CTSK (0.44) | LMNAHSD17B10MAPTHPGDHTT | |
| SCHEMBL29954883 | 0.80 | CTSK (0.44) | LMNAHSD17B10MAPTHPGDHTT | |
| SCHEMBL16492746 | 0.79 | KMT2A (0.37) | LMNAHSD17B10MAPTHPGDHTT | |
| SCHEMBL10072664 | 0.75 | LMNA (0.46) | LMNAHSD17B10MAPK1MAPTMITF | |
| SCHEMBL12491373 | 0.73 | ATR (0.39) | LMNAHSD17B10HTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |