Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957881 | 1.00 | KMT2A (0.51) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL29951363 | 0.87 | LMNA (0.48) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL29957233 | 0.87 | LMNA (0.48) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL29952419 | 0.83 | LMNA (0.51) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL29952820 | 0.83 | LMNA (0.51) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL29954883 | 0.82 | CTSK (0.44) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL29957138 | 0.82 | CTSK (0.44) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL16492746 | 0.81 | KMT2A (0.37) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL15331693 | 0.80 | FAAH (0.34) | ALDH1A1LMNAATM | |
| SCHEMBL19502752 | 0.78 | KMT2A (0.50) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |