Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957138 | 1.00 | CTSK (0.44) | CTSKLMNAMEN1KMT2ATSHR | |
| SCHEMBL29957231 | 0.82 | KMT2A (0.51) | CTSKLMNAMEN1KMT2ATSHR | |
| SCHEMBL29957881 | 0.82 | KMT2A (0.51) | CTSKLMNAMEN1KMT2ATSHR | |
| SCHEMBL29952820 | 0.81 | LMNA (0.51) | CTSKLMNAMEN1KMT2ATSHR | |
| SCHEMBL29952419 | 0.81 | LMNA (0.51) | CTSKLMNAMEN1KMT2ATSHR | |
| SCHEMBL29957233 | 0.80 | LMNA (0.48) | CTSKLMNAMEN1KMT2ATSHR | |
| SCHEMBL29951363 | 0.80 | LMNA (0.48) | CTSKLMNAMEN1KMT2ATSHR | |
| SCHEMBL18878153 | 0.74 | ALDH1A1 (0.43) | CTSKLMNAMEN1KMT2ATSHR | |
| SCHEMBL16492746 | 0.74 | KMT2A (0.37) | CTSKLMNAMEN1KMT2ATSHR | |
| SCHEMBL12491373 | 0.71 | ATR (0.39) | LMNAKMT2ATSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |