Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25083506 | 1.00 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL16463746 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL2630762 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL30592272 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL22306049 | 0.79 | LMNA (0.36) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL29951488 | 0.78 | CYP1A2 (0.38) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL6160521 | 0.78 | CYP1A2 (0.38) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL29951145 | 0.75 | NCF1 (0.37) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL3175002 | 0.75 | NCF1 (0.37) | ALDH1A1MEN1KMT2ATDP1LMNA | |
| SCHEMBL18556089 | 0.74 | L3MBTL1 (0.48) | ALDH1A1MEN1KMT2ATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |