Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.63 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.55 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.55 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953225 | 0.88 | ENPP2 (0.57) | ENPP2ORAI1ORAI2ORAI3IDO1 | |
| SCHEMBL3188971 | 0.88 | ENPP2 (0.57) | ENPP2ORAI1ORAI2ORAI3IDO1 | |
| SCHEMBL29595177 | 0.82 | MAPT (0.44) | ENPP2ORAI1ORAI2ORAI3MAPT | |
| SCHEMBL357145 | 0.82 | CA1 (0.61) | IDO1TP53KDM4EALDH1A1LMNA | |
| SCHEMBL2399704 | 0.82 | MAPT (0.44) | ENPP2ORAI1ORAI2ORAI3MAPT | |
| SCHEMBL31116611 | 0.82 | CA1 (0.61) | IDO1TP53KDM4EALDH1A1LMNA | |
| SCHEMBL1492289 | 0.81 | ENPP2 (0.65) | ENPP2ORAI1ORAI2ORAI3IDO1 | |
| SCHEMBL7772568 | 0.81 | ENPP2 (0.65) | ENPP2ORAI1ORAI2ORAI3IDO1 | |
| SCHEMBL23807 | 0.78 | ENPP2 (1.00) | ENPP2ORAI1ORAI2ORAI3TP53 | |
| SCHEMBL29466484 | 0.78 | ENPP2 (1.00) | ENPP2ORAI1ORAI2ORAI3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |