Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 4/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957104 | 0.83 | CXCR1 (0.52) | CXCR1CXCR2ALDH1A1KDM4ETSHR | |
| SCHEMBL20406386 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KDM4ETSHRLMNASMN1; SMN2 | |
| SCHEMBL19145083 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRLMNASMN1; SMN2 | |
| SCHEMBL12889093 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4ETSHRLMNASMN1; SMN2 | |
| SCHEMBL20394335 | 0.78 | LMNA (0.48) | ALDH1A1KDM4ETSHRLMNASMN1; SMN2 | |
| SCHEMBL22941521 | 0.75 | RAB9A (0.43) | ALDH1A1KDM4ETSHRLMNASMN1; SMN2 | |
| SCHEMBL20755032 | 0.75 | BCHE (0.48) | ALDH1A1TSHRLMNASMN1; SMN2RAB9A | |
| SCHEMBL19105550 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KDM4ETSHRLMNASMN1; SMN2 | |
| SCHEMBL29952570 | 0.75 | NR1H2 (0.54) | ALDH1A1TSHRNPC1RAB9AAOC3 | |
| SCHEMBL257905 | 0.71 | CRHBP (0.53) | CXCR1CXCR2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |