Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.40 |
| ▸ | ABAT | P80404 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4310609 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1ALDH1A3PTGS2RAB9A | |
| SCHEMBL29421523 | 0.88 | ALDH1A1 (0.49) | KDM4EALDH1A1ALDH1A3PTGS2RAB9A | |
| SCHEMBL789495 | 0.88 | ALDH1A1 (0.49) | KDM4EALDH1A1ALDH1A3PTGS2RAB9A | |
| SCHEMBL3784501 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1ALDH1A3PTGS2RAB9A | |
| SCHEMBL3783722 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1ALDH1A3PTGS2RAB9A | |
| SCHEMBL31317426 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1PTGS2RAB9AALDH5A1 | |
| SCHEMBL28947075 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1PTGS2RAB9AALDH5A1 | |
| SCHEMBL31500180 | 0.78 | ALDH1A1 (0.57) | KDM4EALDH1A1ALDH1A3PTGS2RAB9A | |
| SCHEMBL30987926 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1PTGS2RAB9ACYP2A6 | |
| SCHEMBL21358481 | 0.78 | ALDH1A3 (0.47) | KDM4EALDH1A1ALDH1A3PTGS2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |