Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.41 |
| ▸ | ABAT | P80404 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3784501 | 0.87 | KDM4E (0.50) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL31317426 | 0.81 | KDM4E (0.59) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL4310609 | 0.81 | KDM4E (0.48) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL29957404 | 0.81 | KDM4E (0.48) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL28947075 | 0.81 | KDM4E (0.59) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL789495 | 0.81 | ALDH1A1 (0.49) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL29421523 | 0.81 | ALDH1A1 (0.49) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL1711479 | 0.79 | KDM4E (0.47) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL21358481 | 0.79 | ALDH1A3 (0.47) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL20995183 | 0.79 | ALDH1A1 (0.57) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | KDM4E 2606/4885PTGS2 3544/4885RAB9A 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.