Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557986 | 0.96 | ENPP2 (0.45) | ENPP2HPGDKDM4EALDH1A1TDP1 | |
| SCHEMBL29957593 | 0.86 | ENPP2 (0.42) | ENPP2KDM4EALDH1A1 | |
| SCHEMBL29951540 | 0.82 | HPGD (0.49) | ENPP2HPGDKDM4EADRB2ADRB1 | |
| SCHEMBL3292159 | 0.82 | NFE2L2 (0.50) | ENPP2HPGDALDH1A1 | |
| SCHEMBL29956831 | 0.79 | ENPP2 (0.51) | ENPP2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29953763 | 0.78 | ENPP2 (0.42) | ENPP2HPGDKDM4EALDH1A1TDP1 | |
| SCHEMBL29951755 | 0.78 | TLR4 (0.49) | ENPP2 | |
| SCHEMBL11171915 | 0.78 | TSHR (0.49) | HPGDALDH1A1LNPEPIGF1R | |
| SCHEMBL2561635 | 0.78 | HPGD (0.44) | ENPP2HPGDADRB2ADRB1ADRB3 | |
| SCHEMBL29957208 | 0.77 | ENPP2 (0.53) | ENPP2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |