Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561635 | 0.95 | HPGD (0.44) | HPGDADRB2ADRB1ADRB3CA1 | |
| SCHEMBL29953257 | 0.85 | AOC2 (0.37) | HPGDCA1CA2ENPP2CYP1A2 | |
| SCHEMBL29957500 | 0.82 | ENPP2 (0.44) | HPGDADRB2ADRB1ADRB3ENPP2 | |
| SCHEMBL320195 | 0.80 | ADRB2 (0.52) | HPGDADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL20869253 | 0.79 | KDM4E (0.59) | HPGDADRB2ADRB1KDM4ECYP1A2 | |
| SCHEMBL11519998 | 0.79 | NFE2L2 (0.63) | HPGDNFE2L2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL19455128 | 0.79 | HPGD (0.52) | HPGDNFE2L2ADRB2ADRB1KDM4E | |
| SCHEMBL7363974 | 0.79 | MEN1 (0.58) | HPGDNFE2L2HIF1ACA1CA2 | |
| SCHEMBL8335852 | 0.78 | HPGD (0.51) | HPGDADRB2ADRB1ADRB3 | |
| SCHEMBL2557986 | 0.78 | ENPP2 (0.45) | HPGDADRB2ADRB1ADRB3ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |