Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557986 | 0.88 | ENPP2 (0.45) | ENPP2ALDH1A1KDM4E | |
| SCHEMBL29957500 | 0.86 | ENPP2 (0.44) | ENPP2ALDH1A1KDM4E | |
| SCHEMBL29953257 | 0.83 | AOC2 (0.37) | ENPP2ALDH1A1TSHRGAAMAPK1 | |
| SCHEMBL19384227 | 0.80 | ENPP2 (0.49) | ENPP2ALDH1A1KDM4E | |
| SCHEMBL29731345 | 0.80 | KDM4E (0.50) | KDM4ETSHRHTTTP53SMN1; SMN2 | |
| SCHEMBL29954310 | 0.80 | SLC2A1 (0.45) | ENPP2ALDH1A1TSHRTP53SMN1; SMN2 | |
| SCHEMBL29956216 | 0.80 | ENPP2 (0.40) | ENPP2ALDH1A1KDM4ETSHRHTT | |
| SCHEMBL29954386 | 0.77 | ENPP2 (0.46) | ENPP2ALDH1A1KDM4E | |
| SCHEMBL29950847 | 0.75 | ENPP2 (0.46) | ENPP2ALDH1A1KDM4E | |
| SCHEMBL4508412 | 0.75 | ENPP2 (0.56) | ENPP2ALDH1A1KDM4ETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |