Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 7/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20975456 | 0.82 | CA1 (0.64) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL1668962 | 0.80 | CA2 (0.59) | CA1CA2CA12CA7CA9 | |
| SCHEMBL27792593 | 0.80 | THRB (0.65) | ERN1TRIM24TRIM33CA1CA2 | |
| Ethane SCHEMBL27592770 | 0.78 | CA1 (0.59) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL6380826 | 0.78 | CA1 (0.39) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL7928539 | 0.77 | TRPA1 (0.59) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7836382 | 0.76 | CA1 (0.71) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL28206869 | 0.76 | ERN1 (0.50) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL29954290 | 0.76 | ERN1 (0.50) | ERN1TRIM24TRIM33CA1CA2 | |
| SCHEMBL2000711 | 0.75 | HSD17B10 (0.46) | ERN1CA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |