SCHEMBL2000711

SCHEMBL2000711

NC(=O)c1c(O)ccc(O)c1C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPT P10636 2/20 0.46
TSHR P16473 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
CA2 P00918 3/20 0.43
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA7 P43166 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
THRB P10828 2/20 0.42
ERN1 O75460 2/20 0.41
LCK P06239 1/20 0.39
POLB P06746 2/20 0.39
PARP1 P09874 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C19 P33261 2/20 0.39
RECQL P46063 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9844924 0.87 KDM4E (0.48) HSD17B10KDM4EMAPTTSHRALDH1A1
SCHEMBL11054505 0.86 HSD17B10 (0.41) HSD17B10KDM4EMAPTTSHRALDH1A1
SCHEMBL1668962 0.82 CA2 (0.59) HSD17B10KDM4EMAPTTSHRALDH1A1
SCHEMBL30366773 0.80 KDM4E (0.46) HSD17B10KDM4EMAPTTSHRALDH1A1
SCHEMBL6360290 0.80 CSNK2A2 (0.40) HSD17B10KDM4EMAPTTSHRALDH1A1
SCHEMBL3453136 0.78 BCAT2 (0.50) HSD17B10KDM4EMAPTTSHRALDH1A1
SCHEMBL7095311 0.77 SELL (0.59) HSD17B10KDM4EMAPTTSHRALDH1A1
SCHEMBL1956878 0.77 KDM4E (0.43) HSD17B10KDM4EMAPTTSHRALDH1A1
SCHEMBL28877395 0.77 ALDH1A1 (0.38) HSD17B10KDM4EMAPTTSHRALDH1A1
SCHEMBL28840578 0.77 KDM4E (0.43) HSD17B10KDM4EMAPTTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071104-A1 Anionic Curable Compositions DESIGNER MOLECULES INC (US) 2026-03-12 US disclosed
US-20260071103-A1 Anionic Curable Compositions DESIGNER MOLECULES INC (US) 2026-03-12 US disclosed
EP-3331959-B1 ANIONIC CURABLE COMPOSITIONS DESIGNER MOLECULES INC (US) 2022-10-05 EP disclosed
CN-108291122-B Anionically curable compositions 设计分子有限公司 2021-01-05 CN disclosed
US-20180237668-A1 ANIONIC CURABLE COMPOSITIONS DESIGNER MOLECULES, INC. 2018-08-23 US disclosed
EP-3331959-A1 ANIONIC CURABLE COMPOSITIONS Designer Molecules, Inc. (US) 2018-06-13 EP disclosed
WO-2017027482-A1 ANIONIC CURABLE COMPOSITIONS DESIGNER MOLECULES, INC. (US) 2017-02-16 WO disclosed
US-7964697-B2 Polyarylether membranes GENERAL ELECTRIC COMPANY (US) 2011-06-21 US disclosed
US-7834134-B2 Polyarylethers, blends and methods for making GENERAL ELECTRIC COMPANY (US) 2010-11-16 US disclosed
WO-2010019331-A1 POLYARYLETHER MEMBRANES GENERAL ELECTRIC COMPANY (US) 2010-02-18 WO disclosed
US-20100041838-A1 POLYARYLETHERS, BLENDS AND METHODS FOR MAKING BL TECHNOLOGIES, INC. 2010-02-18 US disclosed
US-20100041837-A1 POLYARYLETHERS, BLENDS AND METHODS FOR MAKING GENERAL ELECTRIC COMPANY 2010-02-18 US disclosed
US-20100041853-A1 POLYARYLETHER MEMBRANES BL TECHNOLOGIES, INC. 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071104-A1 Anionic Curable Compositions VCL, ITGA8, GABRE HSD17B10 4509/4885KDM4E 41/4885MAPT 1294/4885
US-20260071103-A1 Anionic Curable Compositions CDH1, ESD, SETD2 HSD17B10 4395/4885KDM4E 41/4885MAPT 693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.