SCHEMBL29957587

SCHEMBL29957587

CCNC(=O)CN(C)c1ccc(C=O)cc1[N+](=O)[O-]

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH3A1 P30838 2/20 0.57
ALDH5A1 P51649 1/20 0.45
ABAT P80404 1/20 0.45
HCAR3 P49019 3/20 0.44
ALDH1A1 P00352 7/20 0.43
MAPT P10636 6/20 0.43
SMN1; SMN2 Q16637 5/20 0.43
LMNA P02545 4/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
VCAM1 P19320 1/20 0.42
HPGD P15428 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAPK1 P28482 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2559147 0.88 ALDH3A1 (0.56) ALDH3A1ALDH5A1ABATHCAR3ALDH1A1
SCHEMBL2561640 0.83 ALDH3A1 (0.59) ALDH3A1ALDH5A1ABATHCAR3ALDH1A1
SCHEMBL29956220 0.82 ALDH1A1 (0.46) ALDH3A1ALDH1A1SMN1; SMN2HPGDL3MBTL1
SCHEMBL29955419 0.80 ALDH1A1 (0.44) ALDH3A1ALDH1A1SMN1; SMN2
SCHEMBL29956412 0.80 ERN1 (0.46) ALDH3A1ALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL29950930 0.77 ALDH3A1 (0.74) ALDH3A1ALDH5A1ABATHCAR3ALDH1A1
SCHEMBL29957232 0.75 ALDH1A1 (0.66) ALDH1A1MAPTSMN1; SMN2LMNAKMT2A
SCHEMBL29403345 0.74 ALDH3A1 (0.69) ALDH3A1ALDH5A1ABATHCAR3ALDH1A1
SCHEMBL7142928 0.74 ALDH3A1 (0.69) ALDH3A1ALDH5A1ABATHCAR3ALDH1A1
SCHEMBL10582037 0.74 ALDH3A1 (0.78) ALDH3A1ALDH5A1ABATHCAR3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed