Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556619 | 0.88 | ERN1 (0.48) | ERN1MAPTHTTKDM4ETP53 | |
| SCHEMBL2553715 | 0.82 | ERN1 (0.50) | ERN1MAPTHTTTP53ALDH1A1 | |
| SCHEMBL29956046 | 0.81 | MPO (0.38) | ERN1MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL29957587 | 0.80 | ALDH3A1 (0.57) | MAPTALDH1A1LMNAL3MBTL1ALDH3A1 | |
| SCHEMBL29951605 | 0.78 | ALDH1A1 (0.54) | ERN1MAPTHTTKDM4ETP53 | |
| SCHEMBL29957679 | 0.76 | NOTUM (0.39) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL29953474 | 0.76 | ALDH1A1 (0.53) | ERN1MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL28886073 | 0.75 | ERN1 (0.57) | ERN1MAPTHTTKDM4ETP53 | |
| SCHEMBL4749290 | 0.75 | ERN1 (0.50) | ERN1MAPTHTTKDM4ETP53 | |
| SCHEMBL29956643 | 0.75 | RAB9A (0.46) | ERN1MAPTHTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |