Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953763 | 0.87 | ENPP2 (0.42) | ENPP2ALDH1A1HTTKDM4ETSHR | |
| SCHEMBL29956516 | 0.84 | HRH3 (0.35) | ENPP2ALDH1A1PARP14SMN1; SMN2GAA | |
| SCHEMBL29957593 | 0.80 | ENPP2 (0.42) | ENPP2ALDH1A1HTTKDM4ETSHR | |
| SCHEMBL29954310 | 0.78 | SLC2A1 (0.45) | ENPP2ALDH1A1TSHRTP53SMN1; SMN2 | |
| SCHEMBL29950900 | 0.75 | ENPP2 (0.46) | ENPP2ALDH1A1KDM4EPARP14 | |
| SCHEMBL2555039 | 0.73 | KDM4E (0.60) | ALDH1A1HTTKDM4ETSHRRAB9A | |
| SCHEMBL19384227 | 0.73 | ENPP2 (0.49) | ENPP2ALDH1A1KDM4E | |
| SCHEMBL29951178 | 0.72 | ENPP2 (0.47) | ENPP2ALDH1A1HTTL3MBTL1RAB9A | |
| SCHEMBL29952387 | 0.70 | ALDH1A1 (0.41) | ENPP2ALDH1A1TSHRL3MBTL1RAB9A | |
| SCHEMBL29957056 | 0.70 | RAB9A (0.65) | ENPP2ALDH1A1HTTTSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |