Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | LPL | P06858 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26488577 | 0.85 | ACHE (0.59) | PARP1ENPP2LPLLIPGACHE | |
| SCHEMBL29956004 | 0.83 | PARP1 (0.45) | PARP1TNKSSIGMAR1DRD2HTR2A | |
| SCHEMBL29957545 | 0.80 | LPL (0.47) | ENPP2LPLLIPGACHEMEN1 | |
| SCHEMBL1724355 | 0.79 | SMN1; SMN2 (0.60) | ENPP2LPLLIPG | |
| SCHEMBL29953904 | 0.79 | KDM4E (0.45) | ENPP2LPLLIPG | |
| SCHEMBL3666137 | 0.79 | MC4R (0.57) | ENPP2SIGMAR1LPLLIPG | |
| SCHEMBL29955283 | 0.78 | SMN1; SMN2 (0.63) | ENPP2 | |
| SCHEMBL2248354 | 0.78 | SMN1; SMN2 (0.63) | ENPP2 | |
| Hydrochloric Acid SCHEMBL29955383 | 0.78 | SMN1; SMN2 (0.58) | ENPP2LPLLIPG | |
| SCHEMBL29956692 | 0.78 | MBTD1 (0.50) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |