SCHEMBL29957764

SCHEMBL29957764

Nc1ccc2cccc(C=O)c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.53
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 4/20 0.43
CYP3A4 P08684 3/20 0.43
CASP1 P29466 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
ALOX15 P16050 2/20 0.42
CASP7 P55210 2/20 0.42
HBB P68871 1/20 0.42
HIF1A Q16665 1/20 0.42
PLAU P00749 1/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
TYMS P04818 1/20 0.39
CYP2A6 P11509 1/20 0.39
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5748858 0.86 ALDH1A1 (0.55) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL5745458 0.86 ALDH1A1 (0.55) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL4359140 0.85 PLAU (0.53) CTDSP1ALDH1A1HSD17B10CYP3A4CASP1
SCHEMBL31661013 0.78 CYP2A6 (0.49) ALDH1A1TDP1MEN1KMT2ALMNA
SCHEMBL9485988 0.78 CYP2A6 (0.49) ALDH1A1TDP1MEN1KMT2ALMNA
SCHEMBL9883875 0.78 KIF11 (0.42) ALDH1A1HSD17B10TDP1MEN1KMT2A
SCHEMBL1817898 0.77 MEN1 (0.48) ALDH1A1HSD17B10CYP3A4TDP1MEN1
SCHEMBL5748981 0.77 ALDH1A1 (0.43) ALDH1A1HSD17B10CYP3A4TDP1PLAU
SCHEMBL11042152 0.77 ALDH1A1 (0.45) ALDH1A1TDP1MEN1KMT2ALMNA
SCHEMBL11045042 0.77 TDP1 (0.48) TDP1MEN1KMT2ALMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed