Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748858 | 0.86 | ALDH1A1 (0.55) | PLAUALDH1A1HSD17B10CYP3A4CASP1 | |
| SCHEMBL5745458 | 0.86 | ALDH1A1 (0.55) | PLAUALDH1A1HSD17B10CYP3A4CASP1 | |
| SCHEMBL29957764 | 0.85 | CTDSP1 (0.53) | PLAUALDH1A1HSD17B10CYP3A4CASP1 | |
| SCHEMBL9096655 | 0.78 | ERN1 (0.44) | PLAUALDH1A1HSD17B10CYP3A4CASP1 | |
| SCHEMBL1666511 | 0.78 | KIF11 (0.42) | ALDH1A1HSD17B10TDP1KDM4EMEN1 | |
| SCHEMBL1817898 | 0.77 | MEN1 (0.48) | ALDH1A1HSD17B10CYP3A4TDP1KDM4E | |
| SCHEMBL9437612 | 0.77 | CYP1A2 (0.57) | ALDH1A1HSD17B10TDP1KDM4ETSHR | |
| SCHEMBL4866312 | 0.77 | TDP1 (0.48) | HSD17B10TDP1MAPTHTTSMN1; SMN2 | |
| SCHEMBL29955696 | 0.77 | CYP1A2 (0.57) | ALDH1A1HSD17B10TDP1KDM4ETSHR | |
| SCHEMBL9851160 | 0.77 | TYMS (0.45) | PLAUALDH1A1HSD17B10CYP3A4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-2754657-B1 | LUMINESCENT SUBSTRATE FOR LUCIFERASE | UNIV ELECTRO COMMUNICATIONS (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-8962854-B2 | Luminescent substrate for luciferase | THE UNIVERSITY OF ELECTRO-COMMUNICATIONS (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20140221665-A1 | LUMINESCENT SUBSTRATE FOR LUCIFERASE | THE UNIVERSITY OF ELECTRO-COMMUNICATIONS (JP) | 2014-08-07 | — | — | US | disclosed |
| EP-2045252-B1 | Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings | LIFE TECHNOLOGIES CORP (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-2045252-A2 | Derivatives of 1,2-dihydro-7-hydroxyquinolines containing fused rings | Molecular Probes, Inc. (US) | 2009-04-08 | — | — | EP | disclosed |
| EP-0323441-B1 | 5-Fluorouracil derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0436902-B1 | 5-Fluorouracil derivatives | OTSUKA PHARMA CO LTD (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-5155113-A | Administering 5-fluorouracil and derivatives with pyridine and pyridone derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |
| EP-0180897-B1 | 5-FLUOROURACIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0436902-A1 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-17 | — | — | EP | disclosed |
| US-4983609-A | Anticancer agents | OTSUKA PHARMACEUTICAL (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4151174-A | 1:1 Adducts of indole and (na)phthalaldehydic acid | POLAROID CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |
| US-4036863-A | Trinapthylmethane compounds | POLAROID CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
| US-3976662-A | 1:1 Adducts of 1-naphthol and (Na)phthalaldehydic acid | POLAROID CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |