Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | CASP1 | P29466 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 2/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748858 | 1.00 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CASP1CYP3A4TDP1 | |
| SCHEMBL29957764 | 0.86 | CTDSP1 (0.53) | ALDH1A1HSD17B10CASP1CYP3A4TDP1 | |
| SCHEMBL4359140 | 0.86 | PLAU (0.53) | ALDH1A1HSD17B10CASP1CYP3A4TDP1 | |
| SCHEMBL30446471 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CASP1CYP3A4TDP1 | |
| SCHEMBL548710 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CASP1CYP3A4TDP1 | |
| SCHEMBL548781 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CASP1CYP3A4TDP1 | |
| SCHEMBL31340003 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CASP1CYP3A4TDP1 | |
| SCHEMBL29392367 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP3A4TDP1HIF1A | |
| SCHEMBL39718 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP3A4TDP1HIF1A | |
| SCHEMBL17422067 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TDP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |