Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677354 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10ALOX15PDE10A | |
| SCHEMBL25899351 | 0.72 | NPC1 (0.42) | ALDH1A1HPGDHSD17B10ALOX15KDM4E | |
| SCHEMBL27924 | 0.71 | NCF1 (0.46) | ALDH1A1HPGDKDM4EGAAMAPT | |
| Phenazine SCHEMBL20658922 | 0.70 | MAPT (0.73) | ALDH1A1HPGDHSD17B10KDM4EGAA | |
| SCHEMBL42594 | 0.70 | BCHE (0.53) | ALDH1A1HPGDHSD17B10ALOX15PDE10A | |
| SCHEMBL29559272 | 0.70 | BCHE (0.53) | ALDH1A1HPGDHSD17B10ALOX15PDE10A | |
| SCHEMBL29966674 | 0.69 | NPC1 (0.63) | ALDH1A1HPGDHSD17B10ALOX15PDE10A | |
| SCHEMBL29614829 | 0.69 | NPC1 (0.63) | ALDH1A1HPGDHSD17B10ALOX15PDE10A | |
| SCHEMBL29942654 | 0.69 | NPC1 (0.63) | ALDH1A1HPGDHSD17B10ALOX15PDE10A | |
| SCHEMBL3076524 | 0.69 | NPC1 (0.63) | ALDH1A1HPGDHSD17B10ALOX15PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |