SCHEMBL42594

SCHEMBL42594

Oc1cnc2ccccc2n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.53
PDE10A Q9Y233 1/20 0.52
ALDH1A1 P00352 5/20 0.52
HPGD P15428 3/20 0.52
HSD17B10 Q99714 2/20 0.52
ALOX15 P16050 1/20 0.52
KDM4E B2RXH2 5/20 0.48
GPR3 P46089 1/20 0.48
MAPT P10636 4/20 0.48
GAA P10253 3/20 0.46
HSP90AA1 P07900 2/20 0.46
HSP90AB1 P08238 2/20 0.46
POLB P06746 1/20 0.46
HTT P42858 2/20 0.45
PDGFRB P09619 1/20 0.45
PDGFRA P16234 1/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ALOX12 P18054 1/20 0.44
MAPK10 P53779 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29559272 1.00 BCHE (0.53) BCHEPDE10AALDH1A1HPGDHSD17B10
SCHEMBL27567277 0.98 BCHE (0.52) BCHEPDE10AALDH1A1HPGDHSD17B10
Methane SCHEMBL27925661 0.98 BCHE (0.52) BCHEPDE10AALDH1A1HPGDHSD17B10
SCHEMBL27344673 0.98 BCHE (0.52) BCHEPDE10AALDH1A1HPGDHSD17B10
Hydrochloric Acid SCHEMBL27656763 0.98 BCHE (0.52) BCHEPDE10AALDH1A1HPGDHSD17B10
SCHEMBL28290991 0.98 BCHE (0.52) BCHEPDE10AALDH1A1HPGDHSD17B10
Hydrochloric Acid SCHEMBL27991312 0.95 BCHE (0.50) BCHEPDE10AALDH1A1HPGDHSD17B10
SCHEMBL27949159 0.88 NPC1 (0.49) BCHEPDE10AALDH1A1HPGDHSD17B10
Fumaric Acid SCHEMBL5758433 0.84 ALDH1A1 (0.53) BCHEALDH1A1HPGDHSD17B10ALOX15
Maleic Acid SCHEMBL5758418 0.84 ALDH1A1 (0.53) BCHEALDH1A1HPGDHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398419-B2 Automated RNA detection using labeled 2′-O-methyl RNA oligonucleotide probes and signal amplification systems VENTANA MEDICAL SYSTEMS, INC. (US) 2025-08-26 US claimed
CN-116554114-B Preparation method of clean 2- (4-hydroxyphenoxy) quinoxaline 山东京博生物科技有限公司 2025-06-17 CN claimed
CN-119822554-A Treatment method of phosphorus-containing wastewater generated in preparation process of sulfonamide compound 佛山市南海北沙制药有限公司 2025-04-15 CN claimed
US-20250066397-A1 PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PAFFAFIN EMBEDDED TISSUE USING CAGED HAPTENS VENTANA MED SYST INC (US) 2025-02-27 US claimed
EP-3341734-B1 PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PAFFAFIN EMBEDDED TISSUE USING CAGED HAPTENS VENTANA MED SYST INC (US) 2024-08-07 EP claimed
CN-118388419-A Preparation method of 2-chloro-7-nitroquinoxaline 武威广达科技有限公司 2024-07-26 CN claimed
CN-118027033-A HDAC6 inhibitor, preparation method thereof and application thereof in anti-inflammatory and ulcerative colitis 四川大学 2024-05-14 CN claimed
EP-3604288-B1 REGIOSELECTIVE ONE-STEP PROCESS FOR SYNTHESIZING 2-HYDROXYQUINOXALINE DEV CT BIOTECHNOLOGY (TW) 2024-04-10 EP claimed
CN-116554114-A Preparation method of clean 2- (4-hydroxyphenoxy) quinoxaline 山东京博生物科技有限公司 2023-08-08 CN claimed
CN-116338167-A Protein proximity assay in formalin fixed paraffin embedded tissue using masked haptens 文塔纳医疗系统公司 2023-06-27 CN claimed
EP-0444619-A2 Process for producing 2-hydroxyquinoxaline derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-09-04 EP claimed
US-4886760-A CHELATE COMPOUND SAVYON DIAGNOSTICS LIMITED (IL) 1989-12-12 US claimed
US-4814444-A SULFIDED PLATINUM, SULFIDED PALLADIUM, OR SULFIDED RHODIUM REDUCING CATALYSTS UNIROYAL CHEMICAL COMPANY, INC. (US) 1989-03-21 US claimed
EP-0295797-A2 Process for the selective reduction of 2-quinoxaline-4-oxides UNIROYAL CHEMICAL COMPANY, Inc. (US) 1988-12-21 EP claimed
EP-0295815-A2 Process for production of 2-quinoxalines UNIROYAL CHEMICAL COMPANY, Inc. (US) 1988-12-21 EP claimed
EP-0271713-A2 Method for preparing aqueous solutions containing chromogenic materials SAVYON DIAGNOSTICS LTD. (IL) 1988-06-22 EP claimed
EP-0253548-A2 Method for the determination of occult blood and chemical compositions therefor SAVYON DIAGNOSTICS LTD. (IL) 1988-01-20 EP claimed
US-4620003-A Process for producing 2-quinoxalinols NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1986-10-28 US claimed
EP-0196743-A2 Stable chemical compositions containing chromogenic materials and peroxides, and method for obtaining them SAVYON DIAGNOSTICS LTD. (IL) 1986-10-08 EP claimed
US-4450271-A Preparation of 2-hydroxyquinoxaline INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1984-05-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066397-A1 PROTEIN PROXIMITY ASSAY IN FORMALIN FIXED PAFFAFIN EMBEDDED TISSUE USING CAGED HAPTENS PAFAH1B2, PAFAH1B3, PAF1 BCHE 1870/4885PDE10A 4406/4885ALDH1A1 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.