Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | IL6 | P05231 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210184 | 1.00 | RAB9A (0.64) | RAB9AMAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL29259228 | 0.84 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL30601063 | 0.84 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL18114422 | 0.83 | AGPAT2 (0.50) | RAB9AMAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL26654543 | 0.82 | RAB9A (0.50) | RAB9AMAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL10829024 | 0.82 | MAPT (0.56) | RAB9AMAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL21612949 | 0.82 | XDH (0.47) | RAB9AMAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL4392862 | 0.81 | RAB9A (0.51) | RAB9AMAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL29958065 | 0.81 | MAPT (0.43) | RAB9AMAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL17161464 | 0.78 | AGPAT2 (0.52) | RAB9AMAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397467-A | Therapeutic agent for tauopathy | 住友制药株式会社 | 2022-11-25 | — | — | CN | disclosed |