Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364307 | 0.85 | LMNA (0.50) | LMNAMEN1MAPTMAPK1KMT2A | |
| SCHEMBL6359113 | 0.83 | LMNA (0.33) | LMNAMEN1MAPTKMT2APDPK1 | |
| SCHEMBL3739911 | 0.78 | MAPT (0.35) | LMNAMEN1MAPTMAPK1KMT2A | |
| SCHEMBL192661 | 0.74 | LMNA (0.55) | LMNAMEN1MAPTKMT2ARAB9A | |
| SCHEMBL3739611 | 0.73 | NLRP3 (0.36) | MEN1MAPTMAPK1KMT2ACCNA2 | |
| SCHEMBL9288161 | 0.72 | ALDH1A1 (0.40) | LMNAMEN1MAPK1KMT2ARAB9A | |
| SCHEMBL13904660 | 0.72 | LMNA (0.36) | LMNARAB9A | |
| SCHEMBL11112327 | 0.69 | ALDH1A1 (0.34) | LMNAMAPK1 | |
| SCHEMBL28264362 | 0.69 | LRRK2 (0.36) | LMNACDK2ADORA2A | |
| SCHEMBL4218323 | 0.68 | KCNH2 (0.37) | LMNACCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |