Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952261 | 0.80 | MAPT (0.54) | KDM4EL3MBTL1ATMALDH1A1HSD17B10 | |
| SCHEMBL14560443 | 0.75 | EGFR (0.64) | KDM4EL3MBTL1TDP1ATMALDH1A1 | |
| SCHEMBL26631823 | 0.72 | L3MBTL1 (0.50) | KDM4EL3MBTL1TDP1ATMALDH1A1 | |
| SCHEMBL1092376 | 0.71 | L3MBTL1 (0.55) | KDM4EL3MBTL1TDP1ATMALDH1A1 | |
| SCHEMBL1520468 | 0.70 | KDM4E (1.00) | KDM4ETDP1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL14560448 | 0.70 | EGFR (0.50) | KDM4EL3MBTL1TDP1ATMALDH1A1 | |
| SCHEMBL28165403 | 0.69 | L3MBTL1 (0.54) | KDM4EL3MBTL1TDP1ATMALDH1A1 | |
| SCHEMBL26631768 | 0.69 | TDP1 (0.54) | KDM4EL3MBTL1TDP1ATMALDH1A1 | |
| SCHEMBL14222653 | 0.69 | L3MBTL1 (0.54) | KDM4EL3MBTL1TDP1ATMALDH1A1 | |
| SCHEMBL28236134 | 0.69 | L3MBTL1 (0.54) | KDM4EL3MBTL1TDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |