Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.54 |
| ▸ | ATM | Q13315 | 4/20 | 0.54 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12499593 | 0.80 | ADORA3 (0.40) | L3MBTL1TDP1ATMLMNAALDH1A1 | |
| SCHEMBL1092376 | 0.79 | L3MBTL1 (0.55) | L3MBTL1TDP1ATMGPR3LMNA | |
| SCHEMBL28441996 | 0.77 | POLB (0.43) | L3MBTL1TDP1ATMLMNAALDH1A1 | |
| SCHEMBL28434024 | 0.77 | CYP1A2 (0.38) | L3MBTL1TDP1ATMLMNAALDH1A1 | |
| SCHEMBL14208571 | 0.77 | ALDH1A1 (0.51) | L3MBTL1TDP1LMNAALDH1A1HTT | |
| SCHEMBL17657914 | 0.76 | PTGER4 (0.43) | L3MBTL1TDP1ATMALDH1A1HTT | |
| SCHEMBL29952236 | 0.76 | ALDH1A1 (0.50) | L3MBTL1TDP1ATMALDH1A1HTT | |
| SCHEMBL8998884 | 0.74 | ALDH1A1 (0.60) | L3MBTL1ATMGPR3LMNAALDH1A1 | |
| SCHEMBL2439142 | 0.74 | GPR3 (0.58) | L3MBTL1GPR3ALDH1A1HTTMAPT | |
| SCHEMBL14222649 | 0.74 | ALDH1A1 (0.50) | L3MBTL1TDP1ATMALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-106928121-B | High-efficiency preparation method of 3-substituted-benzo five-membered heterocycle-2-carbonyl compound | 暨南大学 | 2020-05-12 | — | — | CN | disclosed |
| WO-2008037783-A1 | PROCESS FOR PREPARING 2-OXO-2,5-DIHYDRO-1H-PYRIDO[3,2-B]INDOLE-3-CARBONITRILES | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-04-03 | — | — | WO | disclosed |