Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | PRKACG | P22612 | 1/20 | 0.34 |
| ▸ | PRKACB | P22694 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956044 | 0.75 | CA12 (0.41) | ALOX15TP53SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1626244 | 0.75 | CA12 (0.41) | ALOX15TP53SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29950892 | 0.73 | CCNB2 (0.53) | GAACCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL24522294 | 0.73 | KDM4E (0.46) | ALOX15TP53SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29363427 | 0.73 | KDM4E (0.46) | ALOX15TP53SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29878739 | 0.69 | ALOX15 (0.54) | ALOX15TP53SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1144239 | 0.69 | ALOX15 (0.54) | ALOX15TP53SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29363428 | 0.69 | LMNA (0.51) | ALOX15SMN1; SMN2KDM4EALDH1A1GLA | |
| SCHEMBL22898794 | 0.69 | LMNA (0.51) | ALOX15SMN1; SMN2KDM4EALDH1A1GLA | |
| SCHEMBL19186576 | 0.69 | SRC (0.36) | ERN1KDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |