Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1626244 | 1.00 | CA12 (0.41) | CA12CA9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29363428 | 0.77 | LMNA (0.51) | CA12CA9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29878739 | 0.77 | ALOX15 (0.54) | CA12CA9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1144239 | 0.77 | ALOX15 (0.54) | CA12CA9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL22898794 | 0.77 | LMNA (0.51) | CA12CA9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29958271 | 0.75 | ERN1 (0.41) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL24522320 | 0.74 | KDM4E (0.44) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL16920112 | 0.74 | PIM1 (0.46) | ALDH1A1KMT2ALMNACYP1A2MAPT | |
| SCHEMBL24522294 | 0.74 | KDM4E (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL29950892 | 0.74 | CCNB2 (0.53) | MEN1KMT2ATDP1CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |