Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925739 | 1.00 | PDXK (0.32) | PDXK | |
| SCHEMBL28652978 | 0.82 | CSNK2A1 (0.35) | — | |
| SCHEMBL29957742 | 0.73 | — | — | |
| SCHEMBL22301636 | 0.73 | CYP11B2 (0.35) | — | |
| SCHEMBL23926100 | 0.73 | — | — | |
| SCHEMBL30721099 | 0.73 | CYP11B2 (0.35) | — | |
| SCHEMBL29958587 | 0.72 | TDP1 (0.35) | — | |
| SCHEMBL21050694 | 0.72 | TDP1 (0.35) | — | |
| SCHEMBL29958391 | 0.71 | KMT2A (0.52) | — | |
| SCHEMBL20570729 | 0.70 | MAP3K8 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116390923-A | Heterocyclic derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-115702025-A | Fused tricyclic KRAS inhibitors | 因赛特公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-115124524-A | Tricyclic derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2022198905-A1 | TRICYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2022-09-29 | — | — | WO | disclosed |