SCHEMBL29958716

SCHEMBL29958716

CN(C(=O)/C=C/CC(C)(C)N)[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)N(C)N(C)C

nearest known ligand 0.75

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 8/20 0.64
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
MC4R P32245 2/20 0.35
MC5R P33032 2/20 0.35
MC3R P41968 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL867540 1.00 GHSR (0.64) GHSRPPARGPPARAMMP9MMP8
SCHEMBL867539 1.00 GHSR (0.64) GHSRPPARGPPARAMMP9MMP8
SCHEMBL6320645 0.93 GHSR (0.66) GHSRMMP9MMP8MC4RMC5R
SCHEMBL6325612 0.93 GHSR (0.66) GHSRMMP9MMP8MC4RMC5R
SCHEMBL6320638 0.93 GHSR (0.66) GHSRMMP9MMP8MC4RMC5R
SCHEMBL14433216 0.93 GHSR (0.66) GHSRPPARGPPARAMMP9MMP8
SCHEMBL18472634 0.92 GHSR (0.65) GHSRMMP9MMP8MC4RMC5R
SCHEMBL6424310 0.91 GHSR (0.60) GHSRPPARGPPARAMMP9MMP8
SCHEMBL14003462 0.90 GHSR (0.62) GHSRMMP9MMP8
SCHEMBL3267711 0.90 GHSR (0.75) GHSRMMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260077018-A1 TREATMENT OF MILD TRAUMATIC BRAIN INJURY OXEIA BIOPHARMACEUTICALS INC (US) 2026-03-19 US disclosed
EP-4583902-A2 TREATMENT OF MILD TRAUMATIC BRAIN INJURY Oxeia Biopharmaceuticals, Inc. (US) 2025-07-16 EP disclosed
WO-2024054875-A2 TREATMENT OF MILD TRAUMATIC BRAIN INJURY OXEIA BIOPHARMACEUTICALS, INC. (US) 2024-03-14 WO disclosed
US-20230330187-A1 USE OF GHRELIN OR GHRELIN VARIANT FOR INCREASING DOSE INTENSITY OF CHEMOTHERAPEUTIC AGENTS IN PATIENTS WITH CANCER OXEIA BIOPHARMACEUTICALS INC (US) 2023-10-19 US disclosed
WO-2022226116-A1 GHRELIN TREATMENT OF BRAIN DYSFUNCTION DUE TO VIRAL INFECTION OXEIA BIOPHARMACEUTICALS, INC. (US) 2022-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260077018-A1 TREATMENT OF MILD TRAUMATIC BRAIN INJURY CRH, MYO1G, GHRHR GHSR 6/4885PPARG 845/4885PPARA 968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.